Endocrine Regulations Vol.42, p.53-61, 2008
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Title: SHORT-TERM EFFECT OF SOY CONSUMPTION ON THYROID HORMONE LEVELS AND CORRELATION WITH PHYTOESTROGEN LEVEL IN HEALTHY SUBJECTS |
Author: R. HAMPL, D. OSTATNIKOVA, P. CELEC, Z. PUTZ, O. LAPCÍK, P. MATUCHA |
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Abstract: Objective. Since soy isoflavones may influence the thyroid hormone feedback system by interference with their biosynthesis, secretion and metabolism, we tested whether their controlled shortterm consumption affects thyroid function. Methods. Eighty six volunteers - university students (32 males and 54 females) were eating unprocessed boiled natural soybeans (2 g/kg body weight/day) for 7 consecutive days. Thyrotropin, free thyroid hormones, antibodies to thyroid peroxidase and to thyroglobulin, and actual levels of unconjugated major soy phytoestrogens, daidzein and genistein, were measured in sera collected before, at the end and one week after finishing soy meal consumption. Results. Both phytoestrogens increased significantly (pelate with actual isoflavone levels.
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Keywords: Soy xenoestrogens – Daidzein – Genistein – Thyrotropin – Thyroid hormones – Autoantibodies |
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Year: 2008, Volume: 42, Issue: 2 |
Page From: 53, Page To: 61 |
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