Neoplasma Vol.50, p.97-101, 2003
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Title: Expression of p65, DD3,an c-erbB2 genes in prostate cancer
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Author: E., BALCZERCZAK
; M., MIROWSKI
; A., SASOR
; R., WIERZBICKI
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Abstract: The expression of p65, DD3 and c-erbB2 genes was analyzed in 39 histologically
verified human prostate cancers. The expression of p65 and DD3 genes was
observed in significant percentage in well- and moderately-differentiated
tumors. Both genes expression was lower in poorly differentiated tumors. On the
contrary, c-erbB2 gene expression increased with advanced histological grading
and reached the highest percentage in poorly-differentiated cancers. In the all
investigated groups straight dependence between p65 and DD3 genes expression
occurred. Opposite dependence was noticed in expression of p65/DD3 and c-erbB2
genes.
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Keywords: p65, DD3, c-erbB2, PCR, RT-PCR, prostate cancer.
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Year: 2003, Volume: 50, Issue: |
Page From: 97, Page To: 101 |
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