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Bratislava Medical Journal Vol.118, No.9, p.523-528, 2017 |
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Title: The significance of miR-145 in the prediction of preeclampsia | ||
Author: L. Han, Y. Zhao, Q. Q. Luo, X. X. Liu, S. S. Lu, L. Zou | ||
Abstract: AIM: The aim of this study was to explain the effects of miRNA-145 in the pathogenesis of preeclampsia. In the cell experiments, the proliferation rate was significantly increased, and the cell apoptosis rate was significantly reduced in MC group compared to the MC group (p<0.05, respectively). Comparing with MC group, the PI3K, Akt and mTOR gene and protein expression of miRNA group were significantly up-regulated and the P53 expression was significantly down-regulated (p<0.05, respectively). |
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Keywords: preeclampsia, EVCT, MiR-145, PI3K/Akt/mTOR, P53 | ||
Published online: 18-Oct-2017 | ||
Year: 2017, Volume: 118, Issue: 9 | Page From: 523, Page To: 528 | |
doi:10.4149/BLL_2017_101 |
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