General Physiology and Biophysics Vol.38, No.1, p.83–90, 2019
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Title: Effects of silica-rich water on systemic and peritoneal inflammation in rats exposed to chronic low-level (900-MHz) microwave radiation |
Author: Boris Djindjic, Tanja Dzopalic, Momir Dunjic, Dejan Krstic, Zoran Radovanovic, Jelena Milenkovic, Natasa Djindjic, Biljana Bozic-Nedeljkovic |
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Abstract: Immunomodulating effect of silica-rich water represents a novel field for research, especially regarding its features toward environmental pollutants. The aim of our study was to evaluate the effects of silica-rich water intake on systemic and peritoneal inflammation in rats that were chronically exposed to the low-level microwave (MW) radiation from mobile phones. Wistar Albino rats were exposed to 900 MHz MW radiation for 3 months. The four-treatment model involved rats with standard water (SW) or experimental silica-rich water intake (EW). Peritoneal macrophages (PMs) were harvested using peritoneal lavage and divided into non-stimulated and lipopolysaccharide (LPS) stimulated subgroups. The MW-exposed rats with silica-rich water (MW+EW) had lower serum tumor necrosis factor α (TNF-α) and interleukin 2 (IL-2) levels, but higher IL-10 levels, than MW+SW rats (p
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Keywords: Silicon dioxide, Tumor necrosis factor α, Interleukin 10, Peritoneal macrophages, Adhesion molecules |
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Published online: 04-Feb-2019
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Year: 2019, Volume: 38, Issue: 1 |
Page From: 83, Page To: 90 |
doi:10.4149/gpb_2018032
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