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Bratislava Medical Journal Vol.118, No.2, p.71-76, 2017 |
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Title: Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma | ||
Author: M. O. Kilic, B. Aynekin, A. Kara, D. Icen, K. Demircan | ||
Abstract: OBJECTIVE: The aim is to investigate the expression status of ADAMTS1,8, and 18 proteases in gastric cancer (GC) and lymphatic metastasis. In addition, IRS scores of these three ADAMTS proteases were higher in the metastatic lymph nodes compared with healthy lymph nodes (p < 0.001). The expression status of the three ADAMTSs in cancerous gastric tissue was correlated with stage of tumor. Additionally, ADAMTS1 expression and ADAMTS8 expression in cancerous gastric tissue were found to correlate with grade and tumor size, respectively. |
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Keywords: ADAMTS1, ADAMTS8, ADAMTS18, immunohistochemistry, gastric cancer | ||
Published online: 16-Feb-2017 | ||
Year: 2017, Volume: 118, Issue: 2 | Page From: 71, Page To: 76 | |
doi:10.4149/BLL_2017_014 |
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