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Bratislava Medical Journal Vol.118, No.11, p.684-690, 2017 |
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Title: Decreased circulatory microRNA-4478 as a specific biomarker for diagnosing non-ST-segment elevation myocardial infarction (NSTEMI) and its association with soluble leptin receptor | ||
Author: R. Gholikhani-Darbroud, F. Khaki-Khatibi, F. Mansouri, M. Hajahmadipoorrafsanjani, M. Ghojazadeh | ||
Abstract: OBJECTIVE: This study aimed to assess the usefulness of circulatory microRNA-4478 (miR-4478) and soluble leptin receptor (sLEPR) in prognosis and diagnosis of non-ST-segment elevation myocardial infarction (NSTEMI) and to introduce miR-4478 as a new biomarker for NSTEMI disease. This study aimed also to examine correlation between miR-4478 and soluble leptin receptor and effects of miR-4478 on leptin receptor concentration. There was sensitivity and specificity of 87.5% and 98.8% for miR-4478 and 92.5% and 87.5% for sLEPR. |
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Keywords: microRNA-4478, Leptin receptor, non-ST-segment elevation myocardial infarction, biomarker | ||
Published online: 05-Dec-2017 | ||
Year: 2017, Volume: 118, Issue: 11 | Page From: 684, Page To: 690 | |
doi:10.4149/BLL_2017_129 |
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