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Neoplasma Vol.67, No.1, p.203–208, 2020 |
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Title: Hepatitis B virus infection status is not associated with poor prognosis in classical Hodgkin lymphoma patients | ||
Author: B. Bu, K. Yi, H. Wang, M. Yang, M. Wu, L. Ping, Y. Xie, J. Qiu, L. Zhao, D. Mei, X. Wang, Y. Song, J. Zhu, W. Liu | ||
Abstract: Few studies focused on the relationship between hepatitis B virus (HBV) infection and classical Hodgkin lymphoma (cHL). This study was to evaluate the impact of HBV infection on the treatment outcome and survival of cHL patients. Clinical data of 352 cHL patients treated with ABVD regimen (doxorubicin, bleomycin, vincristine and dacarbazine) between January 2002 and January 2018 were retrospectively collected. According to HBV infection status, the patients were divided into three groups: with HBV infection [hepatitis B surface antigen (HBsAg)-positive], with past HBV infection [HBsAg-negative but anti-hepatitis B core antigen (anti-HBc)-positive], and without HBV infection (HBsAg-negative and anti-HBc-negative). The incidence of HBV infection and past HBV infection in cHL patients were 7.4% (26/352) and 16.5% (58/352), respectively. The median age of patients without HBV infection was lower than those in other two groups (p |
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Keywords: Hodgkin disease, hepatitis B virus, therapeutics, prognosis | ||
Published online: 29-Jan-2020 | ||
Year: 2020, Volume: 67, Issue: 1 | Page From: 203, Page To: 208 | |
doi:10.4149/neo_2019_190211N113 |
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