Neoplasma Vol.51, p.341-344, 2004
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Title: Influence of diet containing lyophilized Enterococcus faecium M-74
with organic selenium on tumor incidence in Apc1638N mice
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Author: K., HLUBINOVA
; B., RYCHLY
; V., ALTANEROVA
; L., EBRINGER
; C., ALTANER
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Abstract: The aim of the present study was to test the effect of long-term
application of diet containing Enterococcus faecium M-74 with
organic selenium on tumor induction in transgenic mice carrying
mutation in Apc gene. Heterozygosity for the Apc1638N mutation in
mice causes development of small intestine and gastric tumors.
Feeding of Apc1638N transgenic mice with enriched diet with
probiotic components during 8 months have shown a minor
therapeutic effect on the clinical manifestations in small
intestine in comparison with control group.
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Keywords: Apc gene mutation, transgenic mice, probiotic diet
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Year: 2004, Volume: 51, Issue: |
Page From: 341, Page To: 344 |
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