General Physiology and Biophysics Vol.26, p.240-242, 2007
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Title: The effect of all-trans retinoic acid and/or colchicine on expression
of rexinoid and thyroid hormone nuclear receptors and their
coregulators in primary rat hepatocytes |
Author: D. Macejova, Z. Dvorak, R. Vrzal, J. Ulrichova, S. Ondkova, J. Brtko |
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Abstract: In the present work, the effects of colchicine (COL) and/or all-trans retinoic acid (ATRA) on expression of rexinoid receptors (RXRs) (α, β, γ), thyroid hormone receptor α and coregulators N-CoR, SMRT and SRC-1 mRNA in primary rat hepatocytes as a model of no-proliferating cells were investigated. Treatment with these components, either alone or in combination, induced differences of the expression profiles between distinct treatment groups.
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Keywords: Nuclear receptors — Transcription factors — Colchicine — ATRA |
Year: 2007, Volume: 26, Issue: |
Page From: 240, Page To: 242 |
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